Liver and Aging 1978
نویسندگان
چکیده
منابع مشابه
GSK3β and aging liver
The loss of regenerative capacity of tissues is one of the major characteristics of aging. Liver represents a powerful system for investigations of mechanisms by which aging reduces regenerative capacity of tissues. The studies within last five years revealed critical role of epigenetic silencing in the inhibition of liver proliferation in old mice. These studies have shown that a number of cel...
متن کاملAnti-Aging Medicine for Liver and Gastroenterology
Anti-Aging Medicine is a branch of preventive medicine that aims to promote a healthy long life. Given that aging itself is a root cause of several diseases of the gut and liver, advances in Anti-Aging Medicine and research may help improve the accuracy of gastroenterological diagnosis and efficacy of treatment. Digestive organ function degrades with age, in line with changes in secretion of ho...
متن کاملLiver Regeneration and Aging: A Current Perspective
Many organ systems exhibit significant age-related deficits, but, based on studies in old rodents and elderly humans, the liver appears to be relatively protected from such changes. A remarkable feature of the liver is its capacity to regenerate its mass following partial hepatectomy. Reports suggests that aging compromises the liver's regenerative capacity, both in the rate and to the extent t...
متن کاملAging and the liver: an update.
The issue of whether or not liver function is compromised in the elderly population remains unresolved. Numerous age-related changes in hepatic structure and function have been described, but many of these observations are qualitative, were made under suboptimal experimental conditions, or are simply contradictory. Changes in hepato-cellular structural parameters, e.g., increased hepatocyte siz...
متن کاملApoptosis in the aging liver
Various changes in the liver during aging can reduce hepatic function and promote liver injury. Aging is associated with high morbidity and a poor prognosis in patients with various liver diseases, including nonalcoholic fatty liver disease, hepatitis C and liver cancer, as well as with surgeries such as partial hepatectomy and liver transplantation. In addition, apoptosis increases with liver ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Gut
سال: 1979
ISSN: 0017-5749
DOI: 10.1136/gut.20.4.348-c